Impact damage tolerance is a frequently listed design requirement for composites hardware. The effect of impact damage and open hole size on laminate compressive strength was studied on sandwich beam specimens which combine CFRP-GFRP hybrid skins and a syntactic foam core. Three test specimen configurations have been investigated for this study. The first two were sandwich beams which were loaded in pure bending (by four point flexure). One series had a skin damaged by impact, and the second series had a circular hole machined through one of the skins. The reduction of compressive strength with increasing damage (hole) size was compared. Additionally a third series of uniaxially loaded open hole compression coupons were tested to generate baseline data for comparison with both series of sandwich beams.